The Future of Skincare: Clinic-Grade at Home with Rejuran

Introduction: From Clinic to Vanity

For years, advanced anti-aging treatments were confined to dermatology clinics and medical spas. Patients invested hundreds — sometimes thousands — in procedures like injectables, microneedling, and regenerative therapies.

But in 2025, a new era is here: clinic-grade skincare at home.

At the center of this revolution is Rejuran, a Korean brand that pioneered the use of PDRN (polydeoxyribonucleotide, derived from salmon DNA) in cosmetic injectables. Once exclusive to professional treatments, this groundbreaking ingredient is now available in serums, creams, and masks you can apply in your own bathroom.

In this guide, we’ll explore:

  • What makes Rejuran and PDRN so powerful

  • How topical formulas compare to in-clinic procedures

  • The best Rejuran products to try in 2025

  • How to integrate them into a smart, anti-aging routine

  • Pro tips for combining Rejuran with devices like the Medicube Booster Pro

Section 1: What Is Rejuran?

Rejuran is a Korean dermo-cosmetic brand originally known for its Rejuran Healer injectable treatment — a clinical procedure where PDRN is injected into the dermis to promote repair, regeneration, and anti-aging.

The Science Behind Rejuran

  • PDRN (Polydeoxyribonucleotide): A DNA fragment extracted from salmon, clinically shown to stimulate fibroblast activity, accelerate wound healing, and promote collagen production.

  • Biocompatibility: Salmon DNA closely resembles human DNA, making it safe and effective for skin integration.

  • Multi-Functional Benefits: Anti-aging, barrier repair, pigmentation correction, and hydration.

Today, Rejuran has translated this science into topical skincare products — allowing users to experience similar regenerative benefits at home.

Section 2: The Benefits of PDRN for Skin

PDRN is not just a buzzword — it’s backed by clinical research. Here’s what it does for your skin:

  1. Cell Regeneration → Stimulates DNA synthesis in fibroblasts, encouraging skin renewal.

  2. Collagen Production → Improves firmness, reduces wrinkles, and restores elasticity.

  3. Barrier Repair → Enhances recovery from environmental stress, acne scars, and sensitivity.

  4. Anti-Inflammatory Effects → Calms redness, irritation, and post-procedure sensitivity.

  5. Hydration → Improves skin’s natural moisture retention.

💡 Think of PDRN as giving your skin “instructions” to repair and renew itself — like pressing reset at a cellular level.

Section 3: Rejuran Products for At-Home Use (2025 Lineup)

Unlike injectables, Rejuran’s skincare range is needle-free, safe, and effective for daily use. Here are some standout products:

1. Rejuran Healer Turnover Ampoule

  • A concentrated serum that accelerates skin turnover.

  • Best for: Wrinkles, dullness, post-procedure recovery.

  • Pair with: Medicube Booster Pro HEAT mode for deeper absorption.

2. Rejuran Healer Healing Mask

  • Infused sheet mask with high-dose PDRN.

  • Best for: SOS recovery after exfoliation or skin irritation.

  • Pair with: Booster Pro COOL mode for calming.

3. Rejuran Intensive Eye Cream

  • Targets fine lines, puffiness, and dark circles around the eyes.

  • Best for: Delicate skin that needs elasticity support.

  • Pair with: Booster Pro MICROCURRENT (low setting) under eyes.

4. Rejuran Healer Turnover Cream

  • Rich cream that locks in ampoules and serums.

  • Best for: Barrier repair and overnight recovery.

5. Rejuran UV Protection Cream & Water Capsule Sun Serum

  • Sunscreens with added DNA repair actives.

  • Best for: Daytime protection + long-term anti-aging.

Section 4: Clinic Treatments vs At-Home Rejuran

Aspect Clinic Injectables Rejuran Topical Skincare
Delivery Injected into dermis Absorbed through skin surface
Downtime Redness, swelling, 2–3 days None
Cost $300–$600 per session $50–$120 per product
Benefits Faster, stronger regeneration Gradual, safe for daily use
Best For Severe aging, scars Maintenance, prevention, mild-moderate concerns

💡 Pro Strategy: Use Rejuran skincare daily and consider occasional clinic treatments if needed — they complement each other.

Section 5: How to Build a Rejuran Routine

Morning (Protection + Glow)

  1. Gentle Cleanser

  2. Hydrating toner (Anua Heartleaf or One Thing Centella)

  3. Rejuran Healer Turnover Ampoule

  4. Booster Pro HEAT mode (2–3 minutes)

  5. Rejuran UV Protection Cream or Water Capsule Sun Serum

Evening (Repair + Anti-Aging)

  1. Double Cleanse

  2. Exfoliating serum (Cellphomed Hydra PHA, 2x/week)

  3. Rejuran Healer Turnover Ampoule

  4. Booster Pro MICROCURRENT mode (5 minutes)

  5. Rejuran Healer Turnover Cream

  6. Optional: Rejuran Healing Mask (2x/week)

Eye Care (Daily)

  • Apply Rejuran Intensive Eye Cream morning and night.

  • For extra lift, use Booster Pro MICROCURRENT (low setting) around the orbital bone.

Section 6: Pro Tips for Maximizing Results

  • Consistency is key: PDRN works gradually, so daily use is essential.

  • Pair with SPF: PDRN repairs DNA damage — but sunscreen prevents it in the first place.

  • Alternate with retinoids: Use Rejuran on “rest nights” when not using retinol to support barrier repair.

  • Use devices wisely: Heat mode for absorption, Cool mode for calming, Microcurrent for lifting.

Section 7: FAQs

Q: How long until I see results with Rejuran skincare?
A: Most users notice smoother, more hydrated skin within 2–3 weeks. Anti-aging effects (reduced wrinkles, improved elasticity) take 6–8 weeks.

Q: Is Rejuran safe for sensitive skin?
A: Yes. PDRN is anti-inflammatory and often recommended for post-procedure recovery.

Q: Can I use Rejuran with retinol or acids?
A: Yes, but not in the same routine. Alternate nights or apply Rejuran in the morning and actives at night.

Q: Is topical PDRN as strong as injections?
A: No — but it provides steady, cumulative benefits without downtime, making it ideal for maintenance.

Conclusion: The Future Is Regenerative

Rejuran represents the future of skincare — moving beyond surface hydration into true cellular regeneration. With PDRN technology, you can now experience clinic-grade anti-aging results at home, safely and consistently.

✨ Whether you’re just starting your anti-aging journey or maintaining post-clinic results, Rejuran offers science-backed solutions that work.

👉 Explore our Rejuran-powered Anti-Aging Sets, designed to pair perfectly with the Medicube Booster Pro, and bring the power of medical innovation to your daily routine.

Back to blog

Leave a comment